Characters who is the main antagonist of a single installment or certain arc or arcs of a series.
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Rob (The Amazing World of Gumball) -
Dr. Ivo Robotnik (Sonic Cinematic Universe) -
Donquixote Doflamingo -
Anakin Skywalker -
Azula -
Emperor Ganishka -
Emperor Palpatine -
Ares (God of War)
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